Vascular And Diabetic Eye Disease 2 Saturday 19 May 11:00 - 12:30 Salle Camille Blanc
E. Ozkilic, A. Altinsoy, A. Ertan,
TURKEY
Effect of cataract surgery combined with intravitreal bevacizumab injection on progression of diabetic retinopathy
Purpose: To study the effect of cataract surgery with intravitreal bevacizumab injection on progression of diabetic retinopathy. Setting: Kudret Eye Hospital, Ankara, Turkey. Methods: Cataract surgery with phacoemulsification was performed in 18 eyes of 12 patients who had diabetic retinopathy. At the end of the surgery 1,25mg (0,05 ml) of bevacizumab was injected intravitreally. All eyes had moderate to severe diabetic retinopathy findings including ischemic findings such as new vessels at disc and/or new vessels elsewhere or hypoxic areas in fundus fluoresein angiography. Outcomes were assessed 6 months postoperatively and included visual acuity (VA), progression of retinopathy and incidence of clinically significant macular oedema (CSME). Results: VA improved in 83% of cases, and was beter than 0.4 in 50% of cases. Regresion of retinopathy occured in 89% of cases. Progression of retinopathy occured in 11% of eyes. No patient had development of proliferative diabetic retinopathy in operated eye. CSME occured in 5 eyes (28%). Conclusions: Cataract surgery even performed with modern technics may lead to progression of diabetic retinopathy due to surgical inflammatory reaction. If cataract surgery is combined with intravitreal bevacizumab in preprolifarative or proliferative diabetic retinopathy, progression of the disease may decrease and success rate may increase.
