Rapid Fire Saturday 19 May 08:00 - 09:32 Salle des Princes
I. Mantel, M. Berguiga, A. Ambresin,
SWITZERLAND
Chronic central serous chorioretinopathy treated with photodynamic therapy with visudyne
Introduction: Chronic central serous chorioretinopathy (CSCR) is a disorder with poor visual prognosis after a remitting relapsing course. There is consensus about the best treatment modality. However, photodynamic therapy (PDT) has been reported to improve the anatomical and visual outcome. Methods: Five consecutive patients with chronic CSCR were treated with PDT between April 2004 and November 2006. Inclusion criteria were visual loss, subfoveal fluid and associated hyperfluorescence on ICG angiography. The latter was the treatment area for PDT. Patients were retrospectively analysed for their functional and anatomical outcome. Clinical ophthalmic examination was completed with fluorescein and ICG angiography as well as optical coherence tomography. Results: Patients were treated with one single PDT. Mean follow-up was 6,8 months (range 3-22 months). Mean visual acuity (VA), measured on Snellen scale and recalculated on a logarythmic scale, improved from decimal 0.32 to 0.50 at last follow-up. Subfoveal fluid disappeared in all cases. No recurrence was observed. Discussion: PDT is a relatively new treatment option with promising results in chronic CSCR. Good anatomical outcome is often associated with improved VA. These results support the hypothesis that changes in the choriocapillaris are at least in part responsible for this pathology. Conclusions: Although promising, PDT for chronic CSCR needs to be evaluated in larger studies, with preference in prospective comparative trials.
